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呼吸道合胞病毒(RSV)的流行及影响
In a post COVID-19 world, 人们仍然高度关注呼吸道疾病以及今后RSV季节的情况. 澳门第一赌城在线娱乐尤其认识到保护最弱势群体的重要性.
Among infants and young children, respiratory syncytial virus, usually referred to as RSV, is one of the most common respiratory viruses.1,2 While RSV typically causes mild, cold-like symptoms, 可发展为下呼吸道感染(LRTI)。, such as bronchiolitis and pneumonia in infants, 使其成为12个月以下婴儿住院的主要原因.1-3
RSV causes seasonal epidemics worldwide each year.4-6 虽然这种病毒很普遍，但仍然没有针对所有婴儿的预防选择.4-7 Common hygiene practices such as frequent handwashing, disinfecting surfaces and toys, 以及避免与病人密切接触有助于防止呼吸道合胞病毒的传播.2
RSV can be unpredictable.8 Any infant, whether they’re born healthy and at term, prematurely or with health conditions, can be hospitalised in their first RSV season.9,10 In fact, 许多住院发生在被认为健康的婴儿中，一半住院发生在年龄较大的婴儿中，即在呼吸道合胞病毒季节开始之前出生的婴儿.9-12
Decades of Research in RSV
Despite more than 60 years of research, 科学界一直在努力开发新的RSV预防方案.7 呼吸道合胞病毒的预防仅限于有既往疾病的婴儿，这使得大多数婴儿无法感染这种病毒.7,13
Despite more than 60 years of research, 科学界一直在努力开发新的RSV预防方案.7
At AstraZeneca, together with our partners at Sanofi, 澳门第一赌城在线娱乐多年来一直致力于研究和合作，以改变医学界对待呼吸道合胞病毒的方式.2,7,13
Impact on Infants and Families
这种病毒对Sanne van Barneveld这样的父母来说太真实了, 她是一位母亲，当她的婴儿thjs时，她亲身经历了呼吸道合胞病毒, who was born at term, contracted the virus at just five weeks old.
一开始是感冒症状，结果却恶化了, 桑娜带他去看儿科医生，儿科医生建议他去医院. As an obstetrician, Sanne was already familiar with RSV, 但看着她年幼的儿子与病毒作斗争，最终进了儿科重症监护室，这是一段痛苦的经历.
After spending several days in the hospital, Thijs was discharged and eventually made a full recovery; he is now a happy and healthy three-year-old. 对于Sanne来说，她给其他父母的建议是要知道什么 symptoms of RSV 是为了让他们知道要注意什么，以及当这些症状变得令人担忧时要寻求医疗救助吗.
A Partnership Dedicated to RSV Prevention
任何家长都不应该目睹他们的孩子与这种病毒作斗争, 作为一个科学界，澳门第一赌城在线娱乐有责任努力开发新的解决方案. 澳门第一赌城在线娱乐与赛诺菲的合作体现了重视和促进合作所能取得的进步. All infants need protection against RSV, 澳门第一赌城在线娱乐共同致力于继续澳门第一赌城在线娱乐的研究和开发，以帮助卫生保健提供者改善对这种常见的传染性呼吸道疾病的护理和管理.
References
1. Respiratory Syncytial Virus (RSV). Centers for Disease Control and Prevention. http://www.cdc.gov/rsv/index.html. Accessed May 2022.
2. 呼吸道合胞病毒感染(RSV):婴幼儿. Centers for Disease Control and Prevention. http://www.cdc.gov/rsv/high-risk/infants-young-children.html. Accessed May 2022.
3. Leader S, Kohlhase K. 呼吸道合胞病毒编码的儿科住院情况，1997至1999年. The pediatric infectious disease journal. 2002;21(7):629-32.
4. Piedimonte G, Perez MK. 呼吸道合胞病毒感染和细支气管炎. Pediatr Rev. 2014;35:519-53.
5. Oymar K, et al. Acute bronchiolitis in infants, a review. Scand J Trauma Resusc Emerg Med. 2014;22:23.
6. Shi T, et al. Global, regional, 2015年幼儿呼吸道合胞病毒引起的急性下呼吸道感染的国家疾病负担估计:系统回顾和建模研究. Lancet 2017; 390: 946–58.
7. Villafana T, et al. 针对年轻人和老年人的呼吸道合胞病毒被动和主动免疫. Expert Rev Vaccines. 2017;16:1-39.
8. Bianchini S, Silvestri E, argenttiero A, Fainardi V, Pisi G, Esposito S. 呼吸道合胞病毒在小儿肺炎中的作用. Microorganisms. 2020; 8(12):2048. http://doi.org/10.3390/microorganisms8122048
9. Rha B et al. 2015-2016年幼儿呼吸道合胞病毒相关住院. pediatric. 2020;146(1):e20193611.
10. 李建军，李建军，李建军，等. Estimated Burden of Community-Onset Respiratory Syncytial Virus-Associated Hospitalizations Among Children Aged <2 Years in the United States, 2014-15. Journal of the pediatric Infectious Diseases Society. 2020;9(5):587-95.
11. Reeves RM, Hardelid P, Panagiotopoulos N, Minaji M, Warburton F, peper. 英国婴儿呼吸道合胞病毒(RSV)引起的住院负担:一项数据链接建模研究. The Journal of infection. 2019;78(6):468-75.
12. Demont, C., Petrica, N., Bardoulat, I. et al. 法国幼儿呼吸道感染相关住院的经济和疾病负担, from 2010 through 2018. BMC nfect Dis 21, 730 (2021). http://doi.org/10.1186/s12879-021-06399-8
13. Synagis -产品特性概要(SmPC) - (eMC)[互联网]. Available from: http://www.ema.europa.欧盟/ en /文件/澳门在线赌城娱乐/ synagis-epar-product-information_en.pdf Accessed May 2022.